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Higher Agreement Between Readers with Deep Learning CAD Software for Reporting Pulmonary Nodules on CT

August 1, 2022
2 min

European Journal of Radiology Open 

H.L. Hempel, M.P. Engbersen, J. Wakkie, B.J. van Kelckhoven, W. de Monyé 

Abstract 

Purpose 

The aim was to evaluate the impact of CAD software on the pulmonary nodule management recommendations of radiologists in a cohort of patients with incidentally detected nodules on CT. 

Methods 

For this retrospective study, two radiologists independently assessed 50 chest CT cases for pulmonary nodules to determine the appropriate management recommendation, twice, unaided and aided by CAD with a 6-month washout period. Management recommendations were given in a 4-point grade based on the BTS guidelines. Both reading sessions were recorded to determine the reading times per case. A reduction in reading times per session was tested with a one-tailed paired t-test, and a linear weighted kappa was calculated to assess interobserver agreement. 

Results 

The mean age of the included patients was 65.0 ± 10.9. Twenty patients were male (40 %). For both readers 1 and 2, a significant reduction of reading time was observed of 33.4 % and 42.6 % (p < 0.001, p < 0.001). The linear weighted kappa between readers unaided was 0.61. Readers showed a better agreement with the aid of CAD, namely by a kappa of 0.84. The mean reading time per case was 226.4 ± 113.2 and 320.8 ± 164.2 s unaided and 150.8 ± 74.2 and 184.2 ± 125.3 s aided by CAD software for readers 1 and 2, respectively. 

Conclusion 

A dedicated CAD system for aiding in pulmonary nodule reporting may help improve the uniformity of management recommendations in clinical practice. 

Disclaimers: 

Chest Suite comprises multiple applications including Veye Lung Nodules, Veye Reporting, DeepHealth Chest CT AI, DeepHealth Viewer, DeepHealth Reporting, DeepHealth Worklist and HealthCCSng. Veye Lung Nodules and Veye Reporting are manufactured by Aidence B.V. and distributed by DeepHealth Inc. DeepHealth Viewer is manufactured by eRAD, Inc. and distributed by DeepHealth, Inc, HealthCCSng is manufactured by Nanox AI Ltd. and distributed by DeepHealth, Inc, DeepHealth Chest CT AI is 510(k) pending. 

Any claims made about Chest Suite may reference claims associated with its individual components. 

Not all products and functionalities are commercially available in all countries. For clearance and commercial availability in your geography of functionalities listed and compatibility with other systems, please contact your account manager. 

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